Insulin glargine

Insulin glargine attaches to insulin receptors on the surface of muscle, fat, and liver cells, switching on a signal inside those cells. That signal tells muscle and fat cells to pull sugar out of the bloodstream, and it tells the liver to stop making and releasing extra sugar. What makes this insulin different from regular insulin is how it's made: it starts out dissolved in a slightly acidic liquid, but once injected under the skin it meets the body's normal, less acidic environment and forms tiny clumps that dissolve very slowly and steadily. Because of this slow dissolving, the insulin trickles into the bloodstream gradually over about a full day instead of arriving in a quick burst, giving steady round-the-clock blood sugar control from one daily shot instead of the sharper ups and downs seen with faster insulins.